3610 W. 80th Ln
Merrillville, IN 46410

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3610 W. 80th Ln
Merrillville, IN 46410

Video | The Mechanome

The Mechanome: The missing link between your genes and environment

The Mechanome is a field of study that relates to the mechanical forces experienced by cells and how they influence gene expression and cellular responses. It is a relatively new area of research that has broad implications for our understanding of health and disease. The mechanome is essentially the link between mechanics and biology.


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Mechanotransduction is the process by which cells convert mechanical stimuli into biochemical signals. In other words, it is how cells sense and respond to mechanical forces. This process is essential for many cellular functions, including cell division, differentiation, and migration. Mechanotransduction plays a critical role in tissue development, repair, and regeneration.

Chronic Diseases and Mechanotransduction

Chronic diseases such as diabetes, heart disease, and cancer are increasingly recognized as mechanotransduction diseases. Mechanotransduction plays a critical role in the development and progression of these diseases. For example, obesity exerts mechanical forces on cells, leading to changes in gene expression that promote inflammation and insulin resistance, which can lead to type 2 diabetes. Similarly, the mechanical forces exerted on the heart by high blood pressure can lead to changes in gene expression that promote heart failure.

The Role of Chiropractic in the Mechanome

Chiropractic care has long been associated with the relief of musculoskeletal pain and dysfunction. However, recent research has shown that chiropractic adjustments can also influence mechanotransduction. Chiropractic adjustments stimulate mechanoreceptors in the joints and muscles, sending signals to the brain and spinal cord that can have a profound effect on gene expression and cellular responses.

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At New Life Family Chiropractic Center, we recognize the importance of the Mechanome as a field of research that sheds light on the intricate connection between mechanics and biology. We believe that Mechanotransduction is a crucial factor in promoting health and preventing diseases, and our chiropractic care services aim to enhance this relationship for your optimal wellness. By leveraging our understanding of the mechanome, we can develop innovative approaches to disease prevention and treatment that account for the influence of mechanical forces. Please make an appointment with us today to learn more about how we can support your health journey.


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